“ Clinical experience may be define as making the same mistake with increasing confidence over an impressive number of years”
Definition
A group of systemic infections involving the liver with similar clinical manifestations and caused by different viruses with typically distinctive epidemiological pattern, A,B,C,D,E and G (See Tabular column at the end of unit for comprehensive check).
Prognosis
Depends upon the nature of causative virus, but overall morality is less than % with old people faring worst. Hepatitis A (mokrtallity less than 0.2% \\) does not progress to chronic liver disease. 10% of Hepatitis B and 50% of Hepatitis C, regardless of severity of acute illness progress to chronic (persistence for more than 10 weeks) liver disease and hepatocellular carcinoma.The mortality for acute Hepatitis B is up to 1%, whenever for Hepatitis E in pregnant women it is 10-2-%. With chronic HDV, 70% develop cirrhosis. HEV does not lead to chronic disease. Alcohol abuse is a major contributing factory for chronicity in HBV and HCV.(Autoimmune non-viral Hepatitis simulates chronic active hepatitis and occurs mostly in young to middle-aged women, with features of autoimmunity like hyperglobulinemia, high titre circulating NA, arthralgia, lymphadenopathy, fever, rash amenorrhoea, etc., with mortality. If untreated, as high as 40%. This condition is uncommon and is not detailed).
Treatment
Inadequate Response
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Prevention
Screening of bllod products. Careful disposal of syringes, apparatus in use on patents
